Publication Laka-library:
European Research Reactor Position Paper. Scenario for sustainable Molybdenum-99 production in Europe

AuthorCEA, NCBJ, NRG, PALLAS, RCR, SCK•CEN, TUM
6-07-4-60-46.pdf
DateJune 2018
Classification 6.07.4.60/46 (MISCELLANEOUS - RADIO ISOTOPES - NUCLEAR MEDICINE / MEDICAL APPLICATIONS )
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From the publication:

European Research Reactor Position Paper
Scenario for sustainable Molybdenum-99 production in Europe
by
CEA, NCBJ, NRG, PALLAS, RCR, SCK•CEN and TUM
15 June 2018

Pierre Yves Thro, Jean Pierre Coulon – CEA, France
Grzegorz Krzysztoszek – NCBJ, Poland
Ronald Schram – NRG, the Netherlands
Hermen van der Lugt – PALLAS, the Netherlands
Jan Milcak – RCR, Czech Republic
Leo Sannen, Bernard Ponsard – SCK•CEN, Belgium
Winfried Petry, Heiko Gerstenberg – TUM, FRM II, Germany
Scenario for sustainable Molybdenum-99 production in Europe

SUMMARY
 The European medical community and patients need a reliable continuous supply chain 
for Mo-99/Tc-99m. Since the 2008 crisis the OECD High Level Group on the Security of 
Supply of Medical Radioisotopes (HLG MR), the European Observatory and Association of 
Imaging Producers & Equipment Suppliers (AIPES) support and secure providing and 
sustainable production of Mo-99 based on research reactors. Europe plays the leading 
role in the supply of Mo-99/Tc-99m because it hosts the largest, most coherent and 
coordinated supply chain from the target manufacturing to medical applications.
 For Europe, the European Observatory is the leading body for this coordinated 
approach. Its main strategic objectives are: support a secure Mo-99/Tc-99m supply, 
ensure that the issue of Mo-99/Tc-99m supply is given high political visibility and 
establish periodic reviews of the supply capacities and demand. It is meant to provide 
the coordinated view of the Mo-99/Tc-99m irradiator facilities as a basis for the 
European decision-making process.
 In the next decade, it is expected that several European irradiating reactors will 
shut down. The upcoming capacities of FRM II (Germany) and JHR (France) will be urgently 
needed for the mid-term but to maintain a sustainable supply in the long-term it will be 
necessary to provide for further newly built Mo-99/Tc-99m irradiator facilities.
 To make this economically viable and to encourage investments, full cost recovery 
(FCR) within the production chain is an indispensable condition. For the irradiator 
facilities this means an increase of the price paid for the irradiation services. To 
strengthen the European network all stakeholders should actively participate in the 
coordinated actions of the European Observatory and AIPES.